Preheat the oven to 350℉. Grease and flour (or line with parchment paper) an 8 ½ by 4 ½ inch loaf pan (9 by 5-inch loaf pans also work, it will just be a slightly different shape).
In a large mixing bowl, beat together the sugars, pumpkin puree, vegetable oil and eggs. Add the vanilla extract and mix well.
In a separate bowl, whisk together the dry ingredients: the flour, baking soda, baking powder, salt, cinnamon, ginger, and nutmeg.
In two additions, add the dry mixture to the wet ingredients and mix on low just to combine.
Pour batter into the prepared loaf pan and sprinkle the top of the bread with pumpkin seeds and coarse sugar if using.
Bake for 40-50 minutes until cake tester or toothpick comes out clean.
Cool for 30 minutes in pan on wire rack.